Hypothalamo-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome, and the Eff... - 0 views
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We conclude that the improvement in fatigue seen in some patients with chronic fatigue syndrome during hydrocortisone treatment is accompanied by a reversal of the blunted cortisol responses to human CRH
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These data further suggest that the hypocortisolism found in chronic fatigue syndrome may be secondary to reduced adrenal gland output.
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5-mg replacement dose of hydrocortisone, and the remainder 10 mg
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low dose hydrocortisone therapy (defined as 5-10 mg), in this study, was used to treat CFS. This study found an improvement in symptoms in these patients. Additionally, low cortisol was found in these patients with CFS. Their conclusion, was that low adrenal function is a component of CFS and low dose hydrocortisone therapy is an effective treatment. Now, is the low cortisol as the result of increased metabolism as well?